An Ist rune is a mid rune which can be socketed into equipment in Diablo 2 Resurrected. Although Ist runes are less difficult to obtain than high runes, their magic finding attributes make them valuable enough. Ist Runes grant better chances of magic find than perfect topazes, but this is offset by their relative rarity.


24-IstIst(Number 24)
Clvl Required 51

Weapon: +30% Better Chance of Finding Magical Items
Armor/Helm/Shield: +25% Better Chance of Finding Magical Items

The Countess's extra rune drops on hell difficulty can include Ist runes. The Hellforge on hell difficulty has a 1 in 11 chance to drop an Ist rune as part of its quest reward. The Act 5 (N) Good treasure class has a chance to drop an Ist rune, as do higher Good treasure classes. In single-player, open or ladder games only, the Horadric Cube can transmute two Mal runes and one normal amethyst into one Ist rune.

Ist runes are used in seven rune words.

  • Delirium 'LemIstIo' helm
  • Eternity 'AmnBerIstSolSur' melee weapon
  • Call to Arms 'AmnRalMalIstOhm' weapon
  • Infinity 'BerMalBerIst' polearm (ladder only)
  • Chains of Honor 'DolUmBerIst' body armor
  • Silence 'DolEldHelIstTirVex' weapon
  • Exile 'VexOhmIstDol' paladin-only item

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